Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy | Zendy

SungJan Lin | Zendy; Ruei-Jr Wu | Zendy; HsinYuan Tan | Zendy; Wen Lo | Zendy; WeiChou Lin | Zendy; TaiHorng Young | Zendy; ChihJung Hsu | Zendy; JauShiuh Chen | Zendy; ShiouHwa Jee | Zendy; ChenYuan Dong | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy

Author(s) -

SungJan Lin,

Ruei-Jr Wu,

HsinYuan Tan,

Wen Lo,

WeiChou Lin,

TaiHorng Young,

ChihJung Hsu,

JauShiuh Chen,

ShiouHwa Jee,

ChenYuan Dong

Publication year - 2005

Publication title -

optics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.524

H-Index - 272

eISSN - 1071-2763

pISSN - 0146-9592

DOI - 10.1364/ol.30.002275

Subject(s) - photoaging , autofluorescence , dermis , second harmonic generation , materials science , microscopy , optics , fluorescence , biomedical engineering , dermatology , medicine , pathology , laser , physics

The photoaging process of facial skin is investigated by use of multiphoton fluorescence and second-harmonic generation (SHG) microscopy. We obtain the autofluorescence (AF) and SHG images of the superficial dermis from the facial skin of three patients aged 20, 40, and 70 years. The results show that areas of AF increase with age, whereas areas of SHG decrease with age. The results are consistent with the histological findings in which collagen is progressively replaced by elastic fibers. The AF and SHG changes in photoaging are quantified by a SHG to autofluorescence aging index of dermis (SAAID). Our results suggest that SAAID can be a good indicator of the severity of photoaging.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research