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An opto-acousto-fluidic microscopic system with a high spatiotemporal resolution for microfluidic applications
Author(s) -
Fei Liu,
Tian Jin,
Ruopeng Yan,
Tingting Li,
Biao Hu,
Lei Yao,
Tianye Huang,
Chaolong Song,
Lei Xi
Publication year - 2019
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.27.001425
Subject(s) - galvanometer , frame rate , optics , microfluidics , fluidics , scanner , materials science , microchannel , velocimetry , ultrashort pulse , laser , image resolution , temporal resolution , physics , nanotechnology , engineering , aerospace engineering
In this work, we develop a new opto-acouto-fludic microsopic system, which employs a high-speed one-dimensional galvanometer scanner and an ultrafast pulse laser (600 kHz). The new system has achieved a high two-dimensional frame rate of up to 2500 Hz with a lateral resolution of 1.7 μm and an axial resolution of 36 μm at the imaging plane. To demonstrate the improved performance of the new system compared to our previous one, we carried out experiments to image the flowing droplets generated with T-junction and flow focusing configurations. We also successfully imaged dynamic migration of magneto particles subjected to non-uniform magnetic field in the microchannel. The results suggest that our new system has sufficient spatiotemporal resolutions to carry out studies for high throughput microfluidic applications.

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