Improved detection sensitivity of D-mannitol crystalline phase content using differential spectral phase shift terahertz spectroscopy measurements | Zendy

JeanFrançois Allard | Zendy; Alain Cornet | Zendy; Christophe Debacq | Zendy; Marc Meurens | Zendy; D. Houde | Zendy; Denis Morris | Zendy

Open Access

Improved detection sensitivity of D-mannitol crystalline phase content using differential spectral phase shift terahertz spectroscopy measurements

Author(s) -

JeanFrançois Allard,

Alain Cornet,

Christophe Debacq,

Marc Meurens,

D. Houde,

Denis Morris

Publication year - 2011

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/oe.19.004644

Subject(s) - terahertz radiation , materials science , spectroscopy , phase (matter) , optics , terahertz spectroscopy and technology , terahertz time domain spectroscopy , absorption (acoustics) , differential phase , analytical chemistry (journal) , sensitivity (control systems) , optoelectronics , physics , chemistry , composite material , chromatography , quantum mechanics , electronic engineering , engineering

We report quantitative measurement of the relative proportion of δ- and β-D-mannitol crystalline phases inserted into polyethylene powder pellets, obtained by time-domain terahertz spectroscopy. Nine absorption bands have been identified from 0.2 THz to 2.2 THz. The best quantification of the δ-phase proportion is made using the 1.01 THz absorption band. Coherent detection allows using the spectral phase shift of the transmitted THz waveform to improve the detection sensitivity of the relative δ-phase proportion. We argue that differential phase shift measurements are less sensitive to samples' defects. Using a linear phase shift compensation for pellets of slightly different thicknesses, we were able to distinguish a 0.5% variation in δ-phase proportion.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research