Nanoparticles for highly efficient multiphoton fluorescence bioimaging | Zendy

Laura Martínez Maestro | Zendy; Emma Martín Rodríguez | Zendy; Fiorenzo Vetrone | Zendy; Rafik Naccache | Zendy; H. Loro | Zendy; Daniel Jaque | Zendy; John A. Capobianco | Zendy; J. Garcı́a Solé | Zendy

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Nanoparticles for highly efficient multiphoton fluorescence bioimaging

Author(s) -

Laura Martínez Maestro,

Emma Martín Rodríguez,

Fiorenzo Vetrone,

Rafik Naccache,

H. Loro,

Daniel Jaque,

John A. Capobianco,

J. Garcı́a Solé

Publication year - 2010

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/oe.18.023544

Subject(s) - fluorescence , materials science , nanoparticle , quantum dot , nanotechnology , fluorescence lifetime imaging microscopy , nanorod , infrared , optoelectronics , optics , physics

In this paper, we demonstrate for the first time that the new class of fluoride-based inorganic upconverting nanoparticles, NaYF4:Er3+, Yb3+, are the most efficient multiphoton excited fluorescent nanoparticles developed to date. The near-infrared-to-visible conversion efficiency of the aforementioned nanoparticles surpasses that of CdSe quantum dots and gold nanorods, which are the commercially available inorganic fluorescent nanoprobes presently used for multiphoton fluorescence bioimaging. The results presented here open new perspectives for the implementation of fluorescence tomography by multiphoton fluorescence imaging.

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