All-fiber CARS microscopy of live cells | Zendy

Adrian F. Pegoraro | Zendy; Andrew Ridsdale | Zendy; Douglas J. Moffatt | Zendy; John Paul Pezacki | Zendy; Brian K. Thomas | Zendy; Libin Fu | Zendy; Liang Dong | Zendy; M. E. Fermann | Zendy; Albert Stolow | Zendy

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All-fiber CARS microscopy of live cells

Author(s) -

Adrian F. Pegoraro,

Andrew Ridsdale,

Douglas J. Moffatt,

John Paul Pezacki,

Brian K. Thomas,

Libin Fu,

Liang Dong,

M. E. Fermann,

Albert Stolow

Publication year - 2009

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/oe.17.020700

Subject(s) - optics , fiber laser , materials science , femtosecond , microscopy , laser , second harmonic generation , fiber , optical fiber , photonic crystal fiber , optoelectronics , physics , composite material

Using an all-fiber laser system consisting of a femtosecond Er/Yb fiber oscillator as the pump and an ultra-highly nonlinear fiber for Stokes generation, we demonstrate multimodal (TPF+SHG+CARS) non-linear optical microscopy of both tissue samples and live cells. Multimodal imaging was successfully performed with pixel dwell times as short as 4 micros at low laser powers (< 40 mW total).

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