Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging
Author(s) -
Jang-Woo You,
Teresa C. Chen,
Mircea Mujat,
B. Hyle Park,
Johannes F. de Boer
Publication year - 2006
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.14.006739
Subject(s) - optical coherence tomography , optics , materials science , ghost imaging , preclinical imaging , point spread function , physics , microbiology and biotechnology , in vivo , biology
We present pulsed illumination spectral-domain optical coherence tomography (SD-OCT) for in vivo human retinal imaging. We analyze the signal-to-noise (SNR) for continuous wave (CW) and pulsed illumination SD-OCT. The lateral beam scan motion is responsible for a SNR drop due to lateral scanning induced interference fringe washout. Pulsed illumination can reduce the SNR drop by shorter sample illumination time during the integration time of a camera. First, we demonstrate the SNR benefit of pulsed illumination over CW as function of lateral scan speed for a paper sample. Finally, we show better SNR in retinal images of a normal subject with pulsed illumination SD-OCT over CW at high lateral scanning speed.
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