X-ray phase-contrast microscopy and microtomography
Author(s) -
S. C. Mayo,
Timothy J. Davis,
Timur E. Gureyev,
P. R. Miller,
David M. Paganin,
A. Pogany,
A. W. Stevenson,
S. Wilkins
Publication year - 2003
Publication title -
optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 271
ISSN - 1094-4087
DOI - 10.1364/oe.11.002289
Subject(s) - optics , microscopy , phase contrast microscopy , phase contrast imaging , microscope , phase retrieval , materials science , tomography , phase (matter) , resolution (logic) , contrast (vision) , optical microscope , tomographic reconstruction , scanning electron microscope , physics , fourier transform , quantum mechanics , artificial intelligence , computer science
In-line phase contrast enables weakly absorbing specimens to be imaged successfully with x-rays, and greatly enhances the visibility of fine scale structure in more strongly absorbing specimens. This type of phase contrast requires a spatially coherent beam, a condition that can be met by a microfocus x-ray source. We have developed an x-ray microscope, based on such a source, which is capable of high resolution phase-contrast imaging and tomography. Phase retrieval enables quantitative information to be recovered from phase-contrast microscope images of homogeneous samples of known composition and density, and improves the quality of tomographic reconstructions.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom