Real-time simultaneous single snapshot of optical properties and blood flow using coherent spatial frequency domain imaging (cSFDI) | Zendy

Michael Ghijsen | Zendy; Bernard Choi | Zendy; Anthony J. Durkin | Zendy; Sylvain Gioux | Zendy; Bruce J. Tromberg | Zendy

Open Access

Real-time simultaneous single snapshot of optical properties and blood flow using coherent spatial frequency domain imaging (cSFDI)

Author(s) -

Michael Ghijsen,

Bernard Choi,

Anthony J. Durkin,

Sylvain Gioux,

Bruce J. Tromberg

Publication year - 2016

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.7.000870

Subject(s) - speckle pattern , snapshot (computer storage) , frequency domain , time domain , optics , reactive hyperemia , spatial frequency , image resolution , blood flow , temporal resolution , fourier transform , speckle imaging , optical flow , computer science , physics , computer vision , medicine , image (mathematics) , operating system , quantum mechanics

In this work we present and validate a wide-field method for the real-time mapping of tissue absorption, scattering and blood flow properties over wide regions of tissue (15 cm x 15 cm) with high temporal resolution (50 frames per second). We achieve this by applying Fourier Domain demodulation techniques to coherent spatial frequency domain imaging to extract optical properties and speckle flow index from a single snapshot. Applying this technique to forearm reactive hyperemia protocols demonstrates the ability to resolve intrinsic physiological signals such as the heart beat waveform and the buildup of deoxyhemoglobin associated with oxygen consumption.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research