Open AccessInflammatory Myofibroblastic Tumors in Two Dogs
Author(s) -
Cameron G. Knight,
E. Fan,
Ronald C. Riis,
Sean P. McDonough
Publication year - 2009
Publication title -
veterinary pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.794
H-Index - 89
eISSN - 1544-2217
pISSN - 0300-9858
DOI - 10.1354/vp.46-2-273
Subject(s) - desmin , calponin , vimentin , pathology , immunohistochemistry , actin , population , smooth muscle , antibody , anatomy , medicine , biology , microbiology and biotechnology , immunology , environmental health
Two soft tissue masses from different locations in 2 dogs were submitted for histopathologic examination. Each was well demarcated and consisted of interweaving streams of bland spindle cells among which numerous plasma cells and lymphocytes were scattered. All the spindle cells reacted strongly to antibodies against vimentin and calponin, whereas a subset of the spindle cells expressed smooth muscle actin and desmin. Immunohistochemistry results were consistent with a myofibroblastic derivation for the spindle-cell population and the diagnosis of inflammatory myofibroblastic tumor (IMT) was made. This is the second report of IMT in the veterinary literature.
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