Open AccessHermaphroditism in a Sprague-Dawley Rat
Author(s) -
R. W. Diters,
Kathleen A. Funk,
Huihui Fang,
Stephen K. Durham,
Mark G. Mense
Publication year - 2007
Publication title -
veterinary pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.794
H-Index - 89
eISSN - 1544-2217
pISSN - 0300-9858
DOI - 10.1354/vp.44-3-418
Subject(s) - true hermaphroditism , biology , physiology , toxicity , pathology , medicine , genetics , karyotype , gene , chromosome
A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9–week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the literature.
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