Genome as a Multipurpose Structure Built by Evolution | Zendy

Michel Morange | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Genome as a Multipurpose Structure Built by Evolution

Author(s) -

Michel Morange

Publication year - 2014

Publication title -

perspectives in biology and medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.401

H-Index - 49

eISSN - 1529-8795

pISSN - 0031-5982

DOI - 10.1353/pbm.2014.0008

Subject(s) - extant taxon , genome , encode , biology , function (biology) , evolutionary biology , complexification , epigenetics , computational biology , genetics , gene , mathematical analysis , mathematics

The 2012 publication of the results of the ENCODE program generated an acrimonious debate about the role of junk DNA. This debate is a symptom of the difficulties of dovetailing functional and evolutionary descriptions of genomes. This essay argues that extant genomes are the result of a progressive evolutionary construction. To the basic function that gives rise to RNA and proteins have been successively added additional functions, such as regulation by microRNA and epigenetic marks. This process of complexification was the result of evolutionary history, and different for the different genomes. Better knowledge of the evolutionary history of genomes would help to understand these structures and their functions.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research