Increased susceptibility of S. aureus to ampicillin during exposure to rifampicin: A distinct mechanism of antimicrobial synergism | Zendy

Praseno Praseno | Zendy

Open Access

Increased susceptibility of <em>S. aureus</em> to ampicillin during exposure to rifampicin: A distinct mechanism of antimicrobial synergism

Author(s) -

Praseno Praseno

Publication year - 1997

Publication title -

medical journal of indonesia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.164

H-Index - 9

eISSN - 2252-8083

pISSN - 0853-1773

DOI - 10.13181/mji.v6i2.809

Subject(s) - rifampicin , antimicrobial , ampicillin , microbiology and biotechnology , chemistry , antibiotics , biology

Synergistic affect of ifampisin and ampicillin has been studi.ed on 20 isolates of S. aureus. Isolates used were ampicillin resistent and rifumpicin sensitive' Susceptibility of the isolate to rifampicin was determined with standard broth dilution method and resistance obsert'ed only in p-lactamase positive isolates. We concluded that there is synergistic effect of rifampicin and ampicilinwhich most likely mediated by inhibition of p-lactamase production by rifumpicin.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research