Wuchereria Kalimantani infected Presbytis cristatus (A primate model for drug trials in lymphatic filariasis)
Author(s) -
Purnomo Purnomo,
Bintari Rukmono
Publication year - 1995
Publication title -
medical journal of indonesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.164
H-Index - 9
eISSN - 2252-8083
pISSN - 0853-1773
DOI - 10.13181/mji.v4i2.897
Subject(s) - lymphatic filariasis , wuchereria bancrofti , lymphatic system , biology , drug trial , filariasis , immunology , clinical trial , bioinformatics , helminths
W. kalinantani is a new species, which is norphologically and taxononically related to W. bancrofii. This new species is thefirst nenùer of the genus Wuchereria in which adults have been recovered fron naturally infected nonkey (P. cristatus). Experinents were done to establish the W. knlinantani infected P. cristatus as a prinate nodel in the tertiary screening of new filaricides. The optinal condition and the fixed t,rcnus tolerated by the nonkey was deternined. Optinnl infection was reached with six weekly inoculations of 5O L3 lamae. The prepatent period was about 8 ntonths
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