Muscular effects of relaxin on the mouse colon: mechanical and electrophysiological studies. | Zendy

Roberta Squecco | Zendy; Rachele Garella | Zendy; Fabio Francini | Zendy; Maria C Baccari | Zendy

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Muscular effects of relaxin on the mouse colon: mechanical and electrophysiological studies.

Author(s) -

Roberta Squecco,

Rachele Garella,

Fabio Francini,

Maria C Baccari

Publication year - 2013

Publication title -

italian journal of anatomy and embryology = archivio italiano di anatomia ed embriologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.11

H-Index - 27

ISSN - 1122-6714

DOI - 10.13128/ijae-13901

Relaxin has been reported to influence gastrointestinal motility in mice. However, at present, nothing is known about the effects of relaxin on the electrophysiological properties of the gastrointestinal smooth muscle. In the present experiments relaxin, other than influencing the colonic motility pattern, has been shown to act on cell membrane properties. The results of the present study indicate that relaxin directly modulates the motility of the proximal colon and the membrane potential of smooth muscle.

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