Effects of Nicotine on Spinal Cord Injury Pain: A Randomized, Double-Blind, Placebo Controlled Crossover Trial
Author(s) -
Elizabeth J. Richardson,
J. Scott Richards,
Christopher C. Stewart,
Timothy J. Ness
Publication year - 2012
Publication title -
topics in spinal cord injury rehabilitation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 35
eISSN - 1945-5763
pISSN - 1082-0744
DOI - 10.1310/sci1802-101
Subject(s) - medicine , nicotine , neuropathic pain , placebo , crossover study , anesthesia , spinal cord injury , randomized controlled trial , smoking cessation , chronic pain , exacerbation , physical therapy , spinal cord , psychiatry , alternative medicine , pathology
One factor affecting spinal cord injury (SCI)-related pain may be nicotine. Case reports have described a worsening of neuropathic pain from smoking and relief from abstinence. Neurobiological correlates also implicate the potential effect of nicotine on SCI-related pain.
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