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Conventional Karyotyping and Fluorescence In Situ Hybridization
Author(s) -
Rong He,
Anne E. Wiktor,
Curtis A. Hanson,
Rhett P. Ketterling,
Paul J. Kurtin,
Daniel L. Van Dyke,
Mark R. Litzow,
Matthew H. Howard,
Kaaren K. Reichard
Publication year - 2015
Publication title -
american journal of clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.859
H-Index - 128
eISSN - 1943-7722
pISSN - 0002-9173
DOI - 10.1309/ajcpp6lvmqg4lnck
Subject(s) - karyotype , fluorescence in situ hybridization , biology , concordance , cytogenetics , chromosome , fish <actinopterygii> , genetics , fishery , gene
Cytogenetics defines disease entities and predicts prognosis in acute myeloid leukemia (AML). Conventional karyotyping provides a comprehensive view of the genome, while fluorescence in situ hybridization (FISH) detects targeted abnormalities. The aim of this study was to compare the utility of karyotyping and FISH in adult AML.

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