Open AccessCytogenetic Variation of B-Lymphoblastic Leukemia With Intrachromosomal Amplification of Chromosome 21 (iAMP21)
Author(s) -
Ryan C. Johnson,
Olga Weinberg,
Michael J. Cascio,
Gary V. Dahl,
Bryan Mitton,
Lewis B. Silverman,
Athena M. Cherry,
Daniel A. Arber,
Robert S. Ohgami
Publication year - 2015
Publication title -
american journal of clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.859
H-Index - 128
eISSN - 1943-7722
pISSN - 0002-9173
DOI - 10.1309/ajcpluyf11hqbyrb
Subject(s) - leukemia , cog , lymphoblastic leukemia , chromosome 21 , trisomy , down syndrome , chromosome , medicine , pathology , biology , genetics , artificial intelligence , computer science , gene
B-lymphoblastic leukemia (B-ALL) with intrachromosomal amplification of chromosome 21 (iAMP21) is a relatively uncommon manifestation of acute leukemia and limited predominantly to the pediatric population. Case-specific information regarding flow cytometric, morphologic, and laboratory findings of this subtype of leukemia is currently lacking.