Comparison of DiaSorin and Bio-Rad Test Kits for the Detection of Hepatitis B Virus Total Core and Surface Antibodies on the Bio-Rad Evolis | Zendy

Stephen J. Cavalieri | Zendy; Sharon Hrabovsky | Zendy; Trichel Jorgensen | Zendy

Open Access

Comparison of DiaSorin and Bio-Rad Test Kits for the Detection of Hepatitis B Virus Total Core and Surface Antibodies on the Bio-Rad Evolis

Author(s) -

Stephen J. Cavalieri,

Sharon Hrabovsky,

Trichel Jorgensen

Publication year - 2009

Publication title -

american journal of clinical pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.859

H-Index - 128

eISSN - 1943-7722

pISSN - 0002-9173

DOI - 10.1309/ajcphy8p2loikfbe

Subject(s) - medicine , hepatitis b virus , antibody , virology , virus , immunology

The new MONOLISA Bio-Rad kits were compared to DiaSorin kits for the detection of hepatitis B virus (HBV) total core (HBcTAb) and surface (HBsAb) antibodies on the Bio-Rad Evolis immunoanalyzer. The resolved sensitivities, specificities, positive and negative predictive values, and overall accuracy were 91%, 100%, 100%, 96%, and 97%, respectively, for HBcTAb and 99%, 95%, 96%, 99%, and 97%, respectively, for HBsAb. Whereas accuracy and reagent cost were comparable between the kits, Bio-Rad kits required less specimen volume and less instrument processing time to results than the DiaSorin kits.

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