A versatile model of open-fracture infection | Zendy

Jowan G. Penn-Barwell | Zendy; B Rand | Zendy; K. V. Brown | Zendy; Joseph C. Wenke | Zendy

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A versatile model of open-fracture infection

Author(s) -

Jowan G. Penn-Barwell,

B Rand,

K. V. Brown,

Joseph C. Wenke

Publication year - 2014

Publication title -

bone and joint research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.639

H-Index - 31

ISSN - 2046-3758

DOI - 10.1302/2046-3758.36.2000293

Subject(s) - antibiotics , open fracture , inoculation , medicine , staphylococcus aureus , systemic antibiotics , joint infections , bone infection , infection rate , polymethyl methacrylate , femur , surgery , biology , microbiology and biotechnology , chemistry , orthopedic surgery , bacteria , pathology , polymer , genetics , organic chemistry , periprosthetic , arthroplasty

The purpose of this study was to refine an accepted contaminated rat femur defect model to result in an infection rate of approximately 50%. This threshold will allow examination of treatments aimed at reducing infection in open fractures with less risk of type II error.

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