Open AccessPRIMARY OSTEOARTHRITIS, VENOUSIENGORGEMENT AND OSTEOGENESIS
Author(s) -
Murray Brookes,
Basil Helal
Publication year - 1968
Publication title -
journal of bone and joint surgery. british volume/the journal of bone and joint surgery. british volume
Language(s) - English
Resource type - Journals
eISSN - 0968-7300
pISSN - 0301-620X
DOI - 10.1302/0301-620x.50b3.493
Subject(s) - osteoarthritis , chondrogenesis , medicine , cartilage , subchondral bone , bone formation , primary bone , articular cartilage , primary (astronomy) , surgery , anatomy , pathology , alternative medicine , physics , astronomy
1. The venographic findings in clinical primary osteoarthritis are described. 2. Experimental venous engorgement, of the knee joint and of healing fibular fractures, results in accelerated bone formation and disturbed cartilage formation. 3. Changes in pH, ppCO 2 , and PPO 2 are indicated as the chemical means by which chondrogenesis and osteogenesis can be altered. 4. It is suggested that chronic venous stress in joints is a causal factor in primary osteoarthritis.