Open AccessIs Black Cohosh Estrogenic?
Author(s) -
Gail B. Mahady
Publication year - 2003
Publication title -
nutrition reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.958
H-Index - 150
eISSN - 1753-4887
pISSN - 0029-6643
DOI - 10.1301/nr.2003.may.183-186
Subject(s) - black cohosh , estrogen , estrogen receptor , medicine , mechanism of action , traditional medicine , endocrinology , pharmacology , menopause , biology , biochemistry , breast cancer , cancer , in vitro
Many women seek safe and effective alternative therapies for the treatment of menopausal symptoms. Black cohosh, a botanical product, is one such treatment. Its mechanism of action may involve estrogenic effects, but new data dispute the estrogenic theory and indicate that extracts of black cohosh do not bind to the estrogen receptor, up‐regulate estrogen‐dependent genes, or stimulate the growth of estrogen‐dependent tumors in animal models.