Open AccessCombined Vitamin C and E Supplementation Retards Early Progression of Arteriosclerosis in Heart Transplant Patients
Author(s) -
Liping Liu,
Mohsen Meydani
Publication year - 2002
Publication title -
nutrition reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.958
H-Index - 150
eISSN - 1753-4887
pISSN - 0029-6643
DOI - 10.1301/00296640260385810
Subject(s) - arteriosclerosis , medicine , intravascular ultrasound , cardiology , oxidative stress , disease , transplantation , heart transplantation , coronary arteriosclerosis , coronary heart disease
The development of arteriosclerosis is the limiting factor for the long‐term survival and the major cause of mortality in patients with heart transplants. Various factors, including oxidative stress, contribute to the progression of the disease. In a recent clinical trial using the intravascular ultrasound technique, which detects the early stages of disease development, supplementation with vitamins C and E retarded the progression of coronary arteriosclerosis during the early stage following cardiac transplantation.