Open AccessSynthesis, Structural Characterization and Study of Biological Activity of Hydrazine Derivatives
Author(s) -
Poonam Goklani,
Anil K. Gupta
Publication year - 2017
Publication title -
material science research india
Language(s) - English
Resource type - Journals
eISSN - 2394-0565
pISSN - 0973-3469
DOI - 10.13005/msri/140217
Subject(s) - hydrazide , hydrazone , moiety , biological activity , hydrazine (antidepressant) , chemistry , in vivo , in vitro , combinatorial chemistry , antibacterial activity , proton nmr , stereochemistry , organic chemistry , biochemistry , bacteria , biology , genetics , microbiology and biotechnology
Hydrazide-hydrazone derivatives play vital role in development of various pharmacological activities such as anti-tubercular, antiproliferative and antitumor activities. Some novel biologically active Hydrazide derivatives substituted with heterocyclic moiety have been synthesized. All the synthesized compounds structures were confirmed by IR, NMR and Mass spectra. Synthesized compounds were subjected to antibacterial screening in vitro and biological activity in vivo. Article History Received: 27 July 2017 Accepted: 23 August 2017
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