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Kawasaki Disease: Clinical and Epidemiological Characteristics of Our Cases
Author(s) -
Sibel Bozabalı
Publication year - 2018
Publication title -
turkish journal of pediatric disease
Language(s) - English
Resource type - Journals
eISSN - 1307-4490
pISSN - 2148-3566
DOI - 10.12956/tjpd.2018.329
Subject(s) - epidemiology , kawasaki disease , disease , medicine , pathology , artery
Objective: Our aim was to determine the typical and atypical clinical findings of our cases with Kawasaki Disease (KD). Material and Methods: Patients who were diagnosed as KD between October 2014 and May 2017 were included in the study. The diagnosis of the patients was made according to the criteria of American Heart Association (AHA). results: Nineteen patients with KD were included. The mean age was 33±20 months. 16 patients (84%) were male and 3 patients (16%) were female. The most frequent seasons were winter (n=6, 31.5%) and autumn (n=6, 31.5%). The most common complaint accompanying the fever was rash in 17 patients (89%). Atypical findings such as purulent conjunctivitis were seen in 2 patients and suppurative lymphadenopathy in 2 patients. As a supportive laboratory finding that is particularly important for the diagnosis in incomplete cases, thrombocytosis was seen in 100% of the patients on the 11.5±2.4th day of fever. The coronary artery involvement rate was high and 47% of the patients were positive. Intravenous immunoglobulin (IVIG) and acetylsalicylic acid (ASA) treatment decreased the dimensions of coronary artery dilatation. Although there was no initial coronary involvement in one of our patients, an aneurysm formation was detected 2 years later. conclusion: Coronary artery involvement is more common in our country. Atypical manifestations, such as purulent conjunctivitis and suppurative lymphadenitis, may be encountered and can be difficult to distinguish. One must be careful regarding the clinical and supportive laboratory findings in such patients for effective treatment. Genetic and etiological studies should be emphasized in order to elucidate these differences in patients. The follow-up of the patients is very important for the detection of new aneurysms.

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