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Familial Mediterranean fever (FMF) is an autosomal recessively inherited autoinflammatory disorder that is characterized by recurrent attacks of fever and polyserositis. Approximately 90% of patients are diagnosed in childhood. Typical attacks last for 1-3 days and there is an attack-free period without any complaints. Most common symptoms are fever and abdominal pain. Other common symptoms are chest pain and arthritis due to pleural and synovial involvement. Rash, eye involvement, epididymo-orchitis and glomerulonephritis are rare manifestations of FMF. Herein, we present a case of FMF whose initial symptoms were fever, fatigue and weight loss with high acute phase reactants and abdominal lympadenopathy that was mimicking a malignant process.

A Rare Cause of Lymphadenopathy in Children: Autoinflammatory Disease - Familial Mediterranean Fever