Novel characterisation of mast cell phenotypes from peripheral blood mononuclear cells in chronic fatigue syndrome/myalgic encephalomyelitis patients | Zendy

Thao Nguyen | Zendy; Samantha Johnston | Zendy; Anu Chacko | Zendy; Damien Gibson | Zendy; Julia Cepon | Zendy; Peter Smith | Zendy; Donald Staines | Zendy; Sonya MarshallGradisnik | Zendy

Open Access

Novel characterisation of mast cell phenotypes from peripheral blood mononuclear cells in chronic fatigue syndrome/myalgic encephalomyelitis patients

Author(s) -

Thao Nguyen,

Samantha Johnston,

Anu Chacko,

Damien Gibson,

Julia Cepon,

Peter Smith,

Donald Staines,

Sonya MarshallGradisnik

Publication year - 2016

Publication title -

asian pacific journal of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.405

H-Index - 33

ISSN - 0125-877X

DOI - 10.12932/ap0771

Subject(s) - medicine , immunology , chronic fatigue syndrome , chymase , mast cell , peripheral blood mononuclear cell , encephalomyelitis , tryptase , population , multiple sclerosis , biology , biochemistry , in vitro , environmental health

Mast cells (MCs) mediate inflammation through neuropeptides and cytokines, along with histamine and reactive oxygen species (ROS). Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an illness characterized by an unexplained disabling fatigue with multiple physiological impairments as well as dysregulated cytokine profiles.

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