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Methaemoglobinemia Induced by Poppers and Bupropion Intoxication in the Emergency Department
Author(s) -
Frederico Batista,
Carlos Alves,
Miguel Trindade,
Joana Azevedo Duarte,
Ricardo Rafael Marques
Publication year - 2019
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2019_001072
Subject(s) - medicine , emergency department , bupropion , anesthesia , cocaine use , methylene blue , methemoglobin , emergency medicine , psychiatry , hemoglobin , biochemistry , chemistry , pathology , photocatalysis , smoking cessation , catalysis
Distinguishing toxidromes is critical for adequate treatment of patients with drug intoxication; the most common side effect of bupropion consumption is dose-dependent seizures.The diagnosis of methaemoglobinemia requires a high index of suspicion, particularly in a patient presenting with central cyanosis not responding to supplementary oxygen.Treatment with methylene blue is recommended when the percentage of methaemoglobin is above 30% or when the patient has symptoms related to methaemoglobinemia.

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