Open AccessUse of Mixture Dosing and Nonlinear Mixed Effect Modeling of Eight Environmental Contaminants in Rabbits to Improve Extrapolation Value of Toxicokinetic Data
Author(s) -
Véronique Gayrard,
Jessika Moreau,
Nicole PicardHagen,
Virginie Helies,
Philippe Marchand,
Jean-Philippe Antignac,
PierreLouis Toutain,
Roger Léandri
Publication year - 2021
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp8957
Subject(s) - bioavailability , toxicokinetics , chemistry , tetrachloroethylene , metabolite , environmental chemistry , perfluorooctane , phthalate , hexachlorobenzene , perfluorooctanoic acid , chromatography , pharmacology , pollutant , trichloroethylene , toxicity , organic chemistry , medicine , biochemistry , sulfonate , sodium