Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model | Zendy

Caroline Duval | Zendy; Fatima Teixeira-Clerc | Zendy; Alix F. Leblanc | Zendy; Sothea Touch | Zendy; Claude Emond | Zendy; Michèle Guerre-Millo | Zendy; Sophie Lotersztajn | Zendy; Robert Barouki | Zendy; Μartine Aggerbeck | Zendy; Xavier Coumoul | Zendy

Open Access

Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model

Author(s) -

Caroline Duval,

Fatima Teixeira-Clerc,

Alix F. Leblanc,

Sothea Touch,

Claude Emond,

Michèle Guerre-Millo,

Sophie Lotersztajn,

Robert Barouki,

Μartine Aggerbeck,

Xavier Coumoul

Publication year - 2016

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp316

Subject(s) - medicine , endocrinology , fibrosis , steatosis , fatty liver , aryl hydrocarbon receptor , triglyceride , alanine transaminase , lipid metabolism , hepatic fibrosis , obesity , biology , cholesterol , disease , biochemistry , transcription factor , gene

Exposure to persistent organic pollutants (POPs) has been associated with the progression of chronic liver diseases, yet the contribution of POPs to the development of fibrosis in non-alcoholic fatty liver disease (NAFLD), a condition closely linked to obesity, remains poorly documented.

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