Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress | Zendy

Petra Haberzettl | Zendy; Timothy E. O’Toole | Zendy; Aruni Bhatnagar | Zendy; Daniel J. Conklin | Zendy

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Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress

Author(s) -

Petra Haberzettl,

Timothy E. O’Toole,

Aruni Bhatnagar,

Daniel J. Conklin

Publication year - 2016

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp212

Subject(s) - medicine , insulin resistance , endocrinology , oxidative stress , insulin , protein kinase b , adipose tissue , systemic inflammation , inflammation , insulin receptor , enos , endothelial dysfunction , nitric oxide , nitric oxide synthase , biology , phosphorylation , biochemistry

Epidemiological evidence suggests that exposure to ambient air fine particulate matter (PM2.5) increases the risk of developing type 2 diabetes and cardiovascular disease. However, the mechanisms underlying these effects of PM2.5 remain unclear.

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