Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma | Zendy

Caitlin L. Maikawa | Zendy; Scott Weichenthal | Zendy; Amanda J. Wheeler | Zendy; Nina A. Dobbin | Zendy; Audrey Smargiassi | Zendy; Greg J. Evans | Zendy; Ling Liu | Zendy; Mark S. Goldberg | Zendy; Krystal J. Godri Pollitt | Zendy

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Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma

Author(s) -

Caitlin L. Maikawa,

Scott Weichenthal,

Amanda J. Wheeler,

Nina A. Dobbin,

Audrey Smargiassi,

Greg J. Evans,

Ling Liu,

Mark S. Goldberg,

Krystal J. Godri Pollitt

Publication year - 2016

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp175

Subject(s) - exhaled nitric oxide , interquartile range , oxidative stress , asthma , medicine , glutathione , nitric oxide , reactive oxygen species , physiology , immunology , chemistry , spirometry , biochemistry , enzyme

Epidemiological studies have provided strong evidence that fine particulate matter (PM2.5; aerodynamic diameter ≤ 2.5 μm) can exacerbate asthmatic symptoms in children. Pro-oxidant components of PM2.5 are capable of directly generating reactive oxygen species. Oxidative burden is used to describe the capacity of PM2.5 to generate reactive oxygen species in the lung.

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