Perinatal DDT Exposure Induces Hypertension and Cardiac Hypertrophy in Adult Mice | Zendy

Michele A. La Merrill | Zendy; Sunjay Sethi | Zendy; Ludovic Bénard | Zendy; Erin Moshier | Zendy; Börje Haraldsson | Zendy; Christoph Buettner | Zendy

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Perinatal DDT Exposure Induces Hypertension and Cardiac Hypertrophy in Adult Mice

Author(s) -

Michele A. La Merrill,

Sunjay Sethi,

Ludovic Bénard,

Erin Moshier,

Börje Haraldsson,

Christoph Buettner

Publication year - 2016

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp164

Subject(s) - offspring , captopril , blood pressure , medicine , endocrinology , muscle hypertrophy , angiotensin converting enzyme , physiology , pregnancy , biology , genetics

Dichlorodiphenyltrichloroethane (DDT) was used extensively to control malaria, typhus, body lice, and bubonic plague worldwide, until countries began restricting its use in the 1970s. However, the use of DDT to control vector-borne diseases continues in developing countries. Prenatal DDT exposure is associated with elevated blood pressure in humans.

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