Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos
Author(s) -
Aaron Lulla,
Lisa M. Barnhill,
Gal Bitan,
Magdalena I. Ivanova,
Binh P. Nguyen,
Kelley C. O’Donnell,
Mark Stahl,
Chase Yamashiro,
F.-G. Klarner,
Thomas Schräder,
Alvaro Sagasti,
Jeff M. Bronstein
Publication year - 2016
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp141
Subject(s) - neurotoxicity , toxicity , zebrafish , in vivo , dopaminergic , biology , pharmacology , parkinson's disease , microbiology and biotechnology , chemistry , biochemistry , dopamine , neuroscience , medicine , genetics , disease , organic chemistry , gene
Exposure to the commonly used dithiocarbamate (DTC) pesticides is associated with an increased risk of developing Parkinson disease (PD), although the mechanisms by which they exert their toxicity are not completely understood.
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