Open AccessProlonged Toxicokinetics and Toxicodynamics of Paraquat in Mouse Brain
Author(s) -
Kavita Prasad,
Bożena Winnik,
Mona Thiruchelvam,
Brian Buckley,
Oleg Mirochnitchenko,
Eric K. Richfield
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.9932
Subject(s) - toxicodynamics , toxicokinetics , paraquat , chemistry , pharmacology , environmental chemistry , toxicology , medicine , biology , pharmacokinetics , biochemistry
Paraquat (PQ) has been implicated as a risk factor for the Parkinson disease phenotype (PDP) in humans and mice using epidemiologic or experimental approaches. The toxicokinetics (TK) and toxicodynamics (TD) of PQ in the brain are not well understood.
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