Some aspects of the etiology of non-Hodgkin's lymphoma. | Zendy

Lennart Hardell | Zendy; Gunilla Lindström | Zendy; Bert van Bavel | Zendy; M Fredrikson | Zendy; Göran Liljegren | Zendy

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Some aspects of the etiology of non-Hodgkin's lymphoma.

Author(s) -

Lennart Hardell,

Gunilla Lindström,

Bert van Bavel,

M Fredrikson,

Göran Liljegren

Publication year - 1998

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.98106679

Subject(s) - lymphoma , immunosuppression , etiology , immune system , medicine , immunology , hodgkin lymphoma , immunotoxicology , pathology

In epidemiologic studies, non-Hodgkin's lymphoma (NHL) has been associated with exposure to chemicals such as phenoxyacetic acids; chlorophenols; dioxins; organic solvents including benzene, polychlorinated biphenyls, chlordanes; and immunosuppressive drugs. Experimental evidence and clinical observations indicate that these chemicals may impair the immune system. The risk is increased for NHL in persons with acquired and congenital immune deficiency as well as autoimmune disorders. Also, certain viruses have been suggested to be of etiologic significance for NHL. In some cases of NHL the common mechanism for all these agents and conditions may be immunosuppression, possibly in combination with viruses.

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