Open AccessPrenatal PCB Exposure and Thymus Size at Birth in Neonates in Eastern Slovakia
Author(s) -
Hye Youn Park,
Irva HertzPicciotto,
Ján Petrı́k,
Ľubica Palkovičová,
Anton Kočan,
T. Trnovec
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.9769
Subject(s) - pregnancy , gestational age , physiology , medicine , biology , genetics
Polychlorinated biphenyls (PCBs) are ubiquitous environmental toxicants, for which animal studies demonstrate immunotoxic effects, including thymic atrophy and suppressed immune responses; human investigations of similar end points are sparse. The thymus is essential for the differentiation and maturation of T-cell lymphocytes.
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