Chronic Arsenic Exposure and Cardiac Repolarization Abnormalities with QT Interval Prolongation in a Population-based Study | Zendy

Judy L. Mumford | Zendy; Kegong Wu | Zendy; Yajuan Xia | Zendy; Richard K. Kwok | Zendy; Zhihui Yang | Zendy; James R. Foster | Zendy; William E. Sanders | Zendy

Open Access

Chronic Arsenic Exposure and Cardiac Repolarization Abnormalities with QT Interval Prolongation in a Population-based Study

Author(s) -

Judy L. Mumford,

Kegong Wu,

Yajuan Xia,

Richard K. Kwok,

Zhihui Yang,

James R. Foster,

William E. Sanders

Publication year - 2007

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.9686

Subject(s) - qt interval , prolongation , medicine , repolarization , cardiology , arsenic , long qt syndrome , population , electrocardiography , environmental health , chemistry , electrophysiology , organic chemistry

Chronic arsenic exposure is associated with cardiovascular abnormalities. Prolongation of the QT (time between initial deflection of QRS complex to the end of T wave) interval and profound repolarization changes on electrocardiogram (ECG) have been reported in patients with acute promyelocytic leukemia treated with arsenic trioxide. This acquired form of long QT syndrome can result in life-threatening arrhythmias.

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