Open AccessHormesis and Its Place in Nonmonotonic Dose–Response Relationships: Some Scientific Reality Checks
Author(s) -
Paul Mushak
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.9619
Subject(s) - hormesis , computer science , toxicology , computational biology , medicine , biology , oxidative stress
This analysis is a critical assessment of current hormesis literature. I discuss definitions, characterization, generalizability, mechanisms, absence of empirical data specific for hormesis hypothesis testing, and arguments that hormesis be the "default assumption" in risk assessment.
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