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Effects of estrogenic chemicals on development.
Author(s) -
Lovell A. Jones,
Roman Hájek
Publication year - 1995
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.95103s763
Subject(s) - carcinogen , hormone , estrogen , biology , physiology , disorders of sex development , bioinformatics , endocrinology , genetics
The sum of the evidence supports the necessity to continue to investigate the developmental effects of estrogenic and antiestrogenic compounds when exposure occurs early in life. Additional studies will answer questions relevant to the molecular definition of the developmental or carcinogenic effects of estrogens such as hormone-induced gene alterations. These studies also support the need to use the neonatal mouse model to demonstrate the consequences of reproductive and nonreproductive stem-cell exposure to estrogenic compounds.

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