Baculovirus and insect cell gene expression: review of baculovirus biotechnology.
Author(s) -
Rachel M. Patterson,
James K. Selkirk,
B. Alex Merrick
Publication year - 1995
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.95103756
Subject(s) - microbiology and biotechnology , biopesticide , biology , computational biology , human health , encode , gene , genetics , medicine , environmental health , pesticide , agronomy
The BEVS continues to evolve as a powerful, flexible tool for molecular biology, protein function, and biomedical research. Future developments offer the promise of replacement of hazardous chemical insecticides with environmentally safe biopesticides, construction of baculovirus vectors which encode genes for specific post-translational modifications, and establishment of efficient, stably transformed insect cell lines. FDA approval of BEVS-produced products offer the prospect of new biopharmaceuticals, in particular human therapeutics and vaccines, to improve human health and increase the quality of life for millions of people.
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