Open AccessLead and δ-Aminolevulinic Acid Dehydratase Polymorphism: Where Does It Lead? A Meta-Analysis
Author(s) -
Franco Scinicariello,
Hannah Murray,
Daphne B. Moffett,
Henry Abadin,
Mary Sexton,
Bruce A. Fowler
Publication year - 2006
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.9448
Subject(s) - porphobilinogen synthase , zinc protoporphyrin , lead poisoning , dehydratase , hemoglobin , blood lead level , genotype , creatinine , medicine , chemistry , physiology , lead exposure , heme , biology , biochemistry , enzyme , cats , psychiatry , gene
Lead poisoning affects many organs in the body. Lead inhibits delta-aminolevulinic acid dehydratase (ALAD), an enzyme with two co-dominantly expressed alleles, ALAD1 and ALAD2.
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