Effects of Endocrine Disruptors on Dehydroepiandrosterone Sulfotransferase and Enzymes Involved in PAPS Synthesis: Genomic and Nongenomic Pathways | Zendy

Robert A. Harris | Zendy; Nahid Turan | Zendy; Christopher J. Kirk | Zendy; D. Ramsden | Zendy; R. H. Waring | Zendy

Open Access

Effects of Endocrine Disruptors on Dehydroepiandrosterone Sulfotransferase and Enzymes Involved in PAPS Synthesis: Genomic and Nongenomic Pathways

Author(s) -

Robert A. Harris,

Nahid Turan,

Christopher J. Kirk,

D. Ramsden,

R. H. Waring

Publication year - 2007

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.9365

Subject(s) - sulfotransferase , dehydroepiandrosterone , endocrine system , enzyme , endocrinology , medicine , metabolic pathway , biology , dehydroepiandrosterone sulfate , hormone , chemistry , biochemistry , androgen

Sulfation plays an important role both in detoxification and in the control of steroid activity. Studies in rodents have shown that the conversion of dehydroepiandrosterone (DHEA) to DHEA-sulfate is involved in learning and the memory process.

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