Enhanced Micronucleus Formation and Modulation of Bcl-2:Bax in MCF-7 Cells after Exposure to Binary Mixtures | Zendy

Rebecca Hewitt | Zendy; Albert Forero | Zendy; Paz J. Luncsford | Zendy; Francis L. Martin | Zendy

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Enhanced Micronucleus Formation and Modulation of Bcl-2:Bax in MCF-7 Cells after Exposure to Binary Mixtures

Author(s) -

Rebecca Hewitt,

Albert Forero,

Paz J. Luncsford,

Francis L. Martin

Publication year - 2007

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.9361

Subject(s) - micronucleus test , mcf 7 , chemistry , micronucleus , microbiology and biotechnology , cyp1a2 , lindane , carcinogen , biology , cytochrome p450 , biochemistry , toxicity , cancer cell , genetics , enzyme , cancer , organic chemistry , human breast , pesticide , agronomy

Within mixtures, interactions between different xenobiotics may occur to give rise to additive, synergistic, inhibitory and/or stimulatory effects in target cells. The role that xenobiotics individually or in mixtures, and at environmental concentrations, play in the etiology of common human diseases often remains obscure.

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