Organophosphate Insecticides Target the Serotonergic System in Developing Rat Brain Regions: Disparate Effects of Diazinon and Parathion at Doses Spanning the Threshold for Cholinesterase Inhibition | Zendy

Theodore A. Slotkin | Zendy; Charlotte A. Tate | Zendy; Ian T. Ryde | Zendy; Edward D. Levin | Zendy; Frederic J. Seidler | Zendy

Open Access

Organophosphate Insecticides Target the Serotonergic System in Developing Rat Brain Regions: Disparate Effects of Diazinon and Parathion at Doses Spanning the Threshold for Cholinesterase Inhibition

Author(s) -

Theodore A. Slotkin,

Charlotte A. Tate,

Ian T. Ryde,

Edward D. Levin,

Frederic J. Seidler

Publication year - 2006

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.9337

Subject(s) - diazinon , parathion , organophosphate , serotonergic , cholinesterase , pharmacology , serotonin , 5 ht receptor , chlorpyrifos , chemistry , parathion methyl , neurotransmitter , endocrinology , medicine , receptor , biology , pesticide , biochemistry , agronomy

In the developing brain, serotonin (5HT) systems are among the most sensitive to disruption by organophosphates.

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