Nonrandom distribution of breakpoints in the karyotypes of workers occupationally exposed to benzene. | Zendy

Maria Sąsiadek | Zendy

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Nonrandom distribution of breakpoints in the karyotypes of workers occupationally exposed to benzene.

Author(s) -

Maria Sąsiadek

Publication year - 1992

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.9297255

Subject(s) - karyotype , breakpoint , biology , genetics , chromosome , benzene , distribution (mathematics) , occupational exposure , toxicology , physiology , medicine , chemistry , environmental health , gene , mathematical analysis , mathematics , organic chemistry

The distribution of the breakpoints in the karyotypes of workers occupationally exposed to benzene was tested. Fifty-six workers exposed to benzene were investigated cytogenetically. A significant increase in chromosome aberrations was observed. The distribution of the breakpoints in the karyotypes of examined workers was significantly nonrandom (p less than or equal to 0.001). The breakpoints accumulated mainly on chromosomes 2, 4, and 7.

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