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Animal studies have shown that exposure to common, low-level environmental contaminants [e.g., polychlorinated biphenyls (PCBs), lead] causes excessive and inappropriate responding on intermittent reinforcement schedules. The Differential Reinforcement of Low Rates task (DRL) has been shown to be especially sensitive to low-level PCB exposure in monkeys.

environmental health perspectives

Response Inhibition During Differential Reinforcement of Low Rates (DRL) Schedules May Be Sensitive to Low-Level Polychlorinated Biphenyl, Methylmercury, and Lead Exposure in Children