Panel discussion: mechanisms and health effects of chromium.

The Panel was asked questions that had been prepared prior to the conference as well as queries from the audience, as follows. In response to a question from R. Bartlett as to how CryV can get past the digestive tract without being reduced, M. Costa (New York University Medical Center) stated that it is, in fact, likely reduced. He emphasized that the pharmacokinetics of chromium have not been sufficiently studied. R. Wedeen (Veterans Administration Medical Center, East Orange, New Jersey) was then asked whether exposure to chromium causes increased renal excretion of chromium and of other compounds, a finding which seemed to be alluded to in Mutti's work (1), and if a) this is similar to low molecular weight proteinuria and b) whether the chromium excretion can be correlated with