Induction and progression of human lymphoproliferative lesions by Epstein-Barr virus.
Author(s) -
B. Borisch Chappuis,
H K MüllerHermelink
Publication year - 1990
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.9088237
Subject(s) - mononucleosis , lymphoma , epstein–barr virus , lymphoproliferative disorders , lymphoproliferative disease , virus , herpesviridae , immunology , disease , gammaherpesvirinae , lymphatic system , medicine , virology , pathology , biology , viral disease
Epstein-Barr virus (EBV) is involved in numerous lymphoproliferative diseases. In addition to classical lesions such as endemic Burkitt's lymphoma and infectious mononucleosis, there are other disorders of the lymphoid system that are discussed in relation to EBV: B-cell lymphomas in immunosuppressed individuals. Hodgkin's disease and, to some extent, primary extranodal lymphomas. Studies of the EBV expression in classical and nonclassical lesions could lead to the better understanding of different EBV mechanisms in lymphomagenesis.
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