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Iron, radiation, and cancer.
Author(s) -
RichardG. Stevens,
D.R. Kalkwarf
Publication year - 1990
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.9087291
Subject(s) - cancer , limiting , dietary iron , cancer research , radical , iron deficiency , cancer cell , chemistry , physiology , biology , toxicology , biochemistry , medicine , anemia , mechanical engineering , engineering
Increased iron content of cells and tissue may increase the risk of cancer. In particular, high available iron status may increase the risk of a radiation-induced cancer. There are two possible mechanisms for this effect: iron can catalyze the production of oxygen radicals, and it may be a limiting nutrient to the growth and development of a transformed cell in vivo. Given the high available iron content of the western diet and the fact that the world is changing to the western model, it is important to determine if high iron increases the risk of cancer.

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