The role of free radicals in tumor promotion. | Zendy

Bernard D. Goldstein | Zendy; Brian J. Czerniecki | Zendy; Guillaume Witz | Zendy

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The role of free radicals in tumor promotion.

Author(s) -

Bernard D. Goldstein,

Brian J. Czerniecki,

Guillaume Witz

Publication year - 1989

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.898155

Subject(s) - radical , tumor promotion , promotion (chess) , mechanism (biology) , mechanism of action , chemistry , biology , political science , epistemology , genetics , cancer , biochemistry , carcinogenesis , philosophy , in vitro , politics , law

A role has been suggested for free radicals and active states of oxygen in tumor promotion. There are a number of lines of support for this hypothesis, but no definitive evidence. The hypothesis has proven of value in leading to the development of models pertinent to understanding the mechanism of action of tumor promoters.

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